Sarcoplasmic/endoplasmic reticulum calcium ATPase…

About Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF (STRIT1) is a protein from Homo sapiens identified by UniProt accession P0DN84, 35 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF
UniProt accession	P0DN84
Gene	STRIT1
Organism	Homo sapiens
Length	35 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

Thomsen and Becker disease · score 0.07
adolescent idiopathic scoliosis · score 0.06
Proximal myotonic myopathy · score 0.06
paramyotonia congenita of Von Eulenburg · score 0.05
childhood trauma measurement · score 0.04
pancreatic adenocarcinoma · score 0.04
myotonia congenita, autosomal recessive · score 0.04
cardiomyopathy · score 0.04
breast carcinoma · score 0.04
Dilated cardiomyopathy · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DN84-F1	alphafold	PREDICTED	84.64	—

Amino-acid sequence (35 residues)

MAEKAGSTFS HLLVPILLLI GWIVGCIIMI YVVFS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF (STRIT1)