Ly-6/neurotoxin-like protein 1 (LYNX1)

Homo sapiens — UniProt P0DP58

Gene: LYNX1Homo sapiensSwissProt reviewed

About Ly-6/neurotoxin-like protein 1

Ly-6/neurotoxin-like protein 1 (LYNX1) is a protein from Homo sapiens identified by UniProt accession P0DP58, 116 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.

Target properties

Protein nameLy-6/neurotoxin-like protein 1
UniProt accessionP0DP58
GeneLYNX1
OrganismHomo sapiens
Length116 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (76)

Diseases linked to this target (Open Targets).

  • calcium measurement · score 0.13
  • genetic disorder · score 0.12
  • metabolite measurement · score 0.08
  • fragile X syndrome · score 0.06
  • focal palmoplantar and gingival keratoderma · score 0.05
  • total blood protein measurement · score 0.05
  • Ichthyosis-hypotrichosis syndrome · score 0.05
  • ichthyosis, lamellar, autosomal dominant · score 0.05
  • hereditary palmoplantar keratoderma, Gamborg-Nielsen type · score 0.05
  • ichthyosis hystrix of Curth-Macklin · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P0DP58-F1alphafoldPREDICTED80.37—

Amino-acid sequence (116 residues)

MTPLLTLILV VLMGLPLAQA LDCHVCAYNG DNCFNPMRCP AMVAYCMTTR TYYTPTRMKV SKSCVPRCFE TVYDGYSKHA STTSCCQYDL CNGTGLATPA TLALAPILLA TLWGLL

Explore Ly-6/neurotoxin-like protein 1 with MolForge

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Quick facts

UniProtP0DP58
GeneLYNX1
OrganismHomo sapiens
Length116
Binders0
Diseases76
View on UniProt