Transmembrane and death domain protein 1 (TMDD1)

About Transmembrane and death domain protein 1

Transmembrane and death domain protein 1 (TMDD1) is a protein from Homo sapiens identified by UniProt accession P0DPE3, 317 residues long. MolForge cross-references it against 0 known binders and 1 disease associations.

Target properties

Protein name	Transmembrane and death domain protein 1
UniProt accession	P0DPE3
Gene	TMDD1
Organism	Homo sapiens
Length	317 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (1)

Diseases linked to this target (Open Targets).

chronotype measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DPE3-F1	alphafold	PREDICTED	66.44	—

Amino-acid sequence (317 residues)

MAARTLASAL VLTLWVWALA PAGAVDAMGP HAAVRLAELL TPEECGHFRS LLEAPEPDVE AELSRLSEDR LARPEPLNTT SGSPSRRRRR EAAEDPAGRV AGPGEVSDGC REALAAWLAP QAASLSWDRL ARALRRSGRP DVARELGKNL HQQATLQLRK FGQRFLPRPG AAARVPFAPA PRPRRAAVPA PDWDALQLIV ERLPQPLYER SPMGWAGPLA LGLLTGFVGA LGTGALVVLL TLWITGGDGD RASPGSPGPL ATVQGWWETK LLLPKERRAP PGAWAADGPD SPSPHSALAL SCKMGAQSWG SGALDGL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards