Lymphocyte antigen 6S (LY6S)

About Lymphocyte antigen 6S

Lymphocyte antigen 6S (LY6S) is a protein from Homo sapiens identified by UniProt accession P0DTL4, 134 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.

Target properties

Protein name	Lymphocyte antigen 6S
UniProt accession	P0DTL4
Gene	LY6S
Organism	Homo sapiens
Length	134 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (50)

Diseases linked to this target (Open Targets).

hepatocellular carcinoma · score 0.08
neoplasm · score 0.02
melanoma · score 0.02
lymphoid leukemia · score 0.01
cancer · score 0.01
infect · score 0.01
infection · score 0.01
pituitary tumor · score 0.01
viral disease · score 0.01
acute lymphoblastic leukemia · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DTL4-F1	alphafold	PREDICTED	77.72	—

Amino-acid sequence (134 residues)

MSSLQAMKTL SLVLLVALLS MERAQGLRCY RCLAVLEGAS CSVVSCPFLD GVCVSQKVSV FGSKVRGENK LSLLSCQKDV GFPLLKLTSA VVDSQISCCK GDLCNAVVLA ASSPWALCVQ LLLSLGSVFL WALL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards