Transmembrane protein 276 (TMEM276)

About Transmembrane protein 276

Transmembrane protein 276 (TMEM276) is a protein from Homo sapiens identified by UniProt accession P0DTL5, 192 residues long. MolForge cross-references it against 0 known binders and 1 disease associations.

Target properties

Protein name	Transmembrane protein 276
UniProt accession	P0DTL5
Gene	TMEM276
Organism	Homo sapiens
Length	192 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (1)

Diseases linked to this target (Open Targets).

autosomal recessive non-syndromic intellectual disability · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DTL5-F1	alphafold	PREDICTED	86.70	—

Amino-acid sequence (192 residues)

MAPKPGAEWS TALSHLVLGV VSLHAAVSTA EASRGAAAGF LLQVLAATTT LAPGLSTHED CLAGAWVATV IGLPLLAFDF HWVNGDRSSA NLLLGGGMVL AVAGGHLGPE GRSVAGQAML LVVAVTILIV AVFTANTYGM WGGAMLGVAG LLSRLEEDRL LLLPKEDVCR WALAVGSWAY CRALHTQRLQ WE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards