Protein HRURF (HRURF)

About Protein HRURF

Protein HRURF (HRURF) is a protein from Homo sapiens identified by UniProt accession P0DUH7, 34 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Protein HRURF
UniProt accession	P0DUH7
Gene	HRURF
Organism	Homo sapiens
Length	34 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

hypotrichosis 4 · score 0.60
atrichia with papular lesions · score 0.19
alopecia universalis congenita · score 0.18
Alopecia universalis · score 0.12
inflammatory bowel disease · score 0.06
hypotrichosis · score 0.01
bubonic plague · score 0.01
colitis · score 0.00
Marie Unna hereditary hypotrichosis · score 0.00
Alopecia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DUH7-F1	alphafold	PREDICTED	75.90	—

Amino-acid sequence (34 residues)

MAQPTASAQK LVRPIRAVCR ILQIPESDPS NLRP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards