Serglycin (SRGN)

About Serglycin

Serglycin (SRGN) is a protein from Homo sapiens identified by UniProt accession P10124, 158 residues long. MolForge cross-references it against 0 known binders and 198 disease associations.

Target properties

Protein name	Serglycin
UniProt accession	P10124
Gene	SRGN
Organism	Homo sapiens
Length	158 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (198)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.32
breast adenocarcinoma · score 0.25
basophil percentage of leukocytes · score 0.21
eosinophil count · score 0.18
eosinophil percentage of leukocytes · score 0.14
platelet component distribution width · score 0.11
neoplasm · score 0.11
basophil count · score 0.11
breast cancer · score 0.10
multiple myeloma · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P10124-F1	alphafold	PREDICTED	59.03	—

Amino-acid sequence (158 residues)

MMQKLLKCSR LVLALALILV LESSVQGYPT RRARYQWVRC NPDSNSANCL EEKGPMFELL PGESNKIPRL RTDLFPKTRI QDLNRIFPLS EDYSGSGFGS GSGSGSGSGS GFLTEMEQDY QLVDESDAFH DNLRSLDRNL PSDSQDLGQH GLEEDFML

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards