About Solute carrier family 2, facilitated glucose transporter member 2
Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2) is a protein
from Homo sapiens identified by UniProt accession
P11168, 524 residues long.
MolForge cross-references it against 0 known binders and
292 disease associations.
Target properties
| Protein name | Solute carrier family 2, facilitated glucose transporter member 2 |
|---|
| UniProt accession | P11168 |
|---|
| Gene | SLC2A2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 524 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (292)
Diseases linked to this target (Open Targets).
- glycogen storage disease due to GLUT2 deficiency · score 0.83
- type 2 diabetes mellitus · score 0.69
- body mass index · score 0.47
- glucose measurement · score 0.47
- HbA1c measurement · score 0.45
- triglyceride measurement · score 0.44
- serum gamma-glutamyl transferase measurement · score 0.44
- C-reactive protein measurement · score 0.43
- fasting blood glucose measurement · score 0.43
- lean body mass · score 0.42
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P11168-F1 | alphafold | PREDICTED | 86.65 | — |
Amino-acid sequence (524 residues)
MTEDKVTGTL VFTVITAVLG SFQFGYDIGV INAPQQVIIS HYRHVLGVPL DDRKAINNYV INSTDELPTI SYSMNPKPTP WAEEETVAAA QLITMLWSLS VSSFAVGGMT ASFFGGWLGD TLGRIKAMLV ANILSLVGAL LMGFSKLGPS HILIIAGRSI SGLYCGLISG LVPMYIGEIA PTALRGALGT FHQLAIVTGI LISQIIGLEF ILGNYDLWHI LLGLSGVRAI LQSLLLFFCP ESPRYLYIKL DEEVKAKQSL KRLRGYDDVT KDINEMRKER EEASSEQKVS IIQLFTNSSY RQPILVALML HVAQQFSGIN GIFYYSTSIF QTAGISKPVY ATIGVGAVNM VFTAVSVFLV EKAGRRSLFL IGMSGMFVCA IFMSVGLVLL NKFSWMSYVS MIAIFLFVSF FEIGPGPIPW FMVAEFFSQG PRPAALAIAA FSNWTCNFIV ALCFQYIADF CGPYVFFLFA GVLLAFTLFT FFKVPETKGK SFEEIAAEFQ KKSGSAHRPK AAVEMKFLGA TETV
Explore Solute carrier family 2, facilitated glucose transporter member 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets