Fatty acid-binding protein, intestinal (FABP2)

About Fatty acid-binding protein, intestinal

Fatty acid-binding protein, intestinal (FABP2) is a protein from Homo sapiens identified by UniProt accession P12104, 132 residues long. MolForge cross-references it against 0 known binders and 343 disease associations.

Target properties

Protein name	Fatty acid-binding protein, intestinal
UniProt accession	P12104
Gene	FABP2
Organism	Homo sapiens
Length	132 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (5)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (343)

Diseases linked to this target (Open Targets).

cGMP-specific 3',5'-cyclic phosphodiesterase measurement · score 0.29
reticulocyte count · score 0.24
platelet count · score 0.24
mean corpuscular volume · score 0.23
leukocyte count · score 0.21
myeloid white cell count · score 0.20
blood protein measurement · score 0.16
adolescent idiopathic scoliosis · score 0.16
diastolic blood pressure · score 0.15
appendicular lean mass · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P12104-F1	alphafold	PREDICTED	91.08	—

Amino-acid sequence (132 residues)

MAFDSTWKVD RSENYDKFME KMGVNIVKRK LAAHDNLKLT ITQEGNKFTV KESSTFRNIE VVFELGVTFN YNLADGTELR GTWSLEGNKL IGKFKRTDNG NELNTVREII GDELVQTYVY EGVEAKRIFK KD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards