About Immunoglobulin lambda-like polypeptide 1
Immunoglobulin lambda-like polypeptide 1 (IGLL1) is a protein
from Homo sapiens identified by UniProt accession
P15814, 213 residues long.
MolForge cross-references it against 0 known binders and
175 disease associations.
Target properties
| Protein name | Immunoglobulin lambda-like polypeptide 1 |
|---|
| UniProt accession | P15814 |
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| Gene | IGLL1 |
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| Organism | Homo sapiens |
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| Length | 213 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (175)
Diseases linked to this target (Open Targets).
- isolated agammaglobulinemia · score 0.47
- agammaglobulinemia · score 0.47
- autosomal agammaglobulinemia · score 0.37
- blood protein measurement · score 0.28
- arterial stiffness measurement · score 0.22
- urate measurement · score 0.21
- bone density · score 0.21
- metabolite measurement · score 0.20
- immunoproliferative disorder · score 0.13
- head and neck squamous cell carcinoma · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P15814-F1 | alphafold | PREDICTED | 75.07 | — |
Amino-acid sequence (213 residues)
MRPGTGQGGL EAPGEPGPNL RQRWPLLLLG LAVVTHGLLR PTAASQSRAL GPGAPGGSSR SSLRSRWGRF LLQRGSWTGP RCWPRGFQSK HNSVTHVFGS GTQLTVLSQP KATPSVTLFP PSSEELQANK ATLVCLMNDF YPGILTVTWK ADGTPITQGV EMTTPSKQSN NKYAASSYLS LTPEQWRSRR SYSCQVMHEG STVEKTVAPA ECS
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