Stathmin (STMN1)

About Stathmin

Stathmin (STMN1) is a protein from Homo sapiens identified by UniProt accession P16949, 149 residues long. MolForge cross-references it against 0 known binders and 378 disease associations.

Target properties

Protein name	Stathmin
UniProt accession	P16949
Gene	STMN1
Organism	Homo sapiens
Length	149 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (378)

Diseases linked to this target (Open Targets).

hemoglobin measurement · score 0.29
reticulocyte count · score 0.29
hematocrit · score 0.17
erythrocyte count · score 0.15
BMI-adjusted waist-hip ratio · score 0.15
waist-hip ratio · score 0.14
red blood cell density measurement · score 0.13
neoplasm · score 0.11
hepatocellular carcinoma · score 0.11
non-small cell lung carcinoma · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P16949-F1	alphafold	PREDICTED	88.01	—

Amino-acid sequence (149 residues)

MASSDIQVKE LEKRASGQAF ELILSPRSKE SVPEFPLSPP KKKDLSLEEI QKKLEAAEER RKSHEAEVLK QLAEKREHEK EVLQKAIEEN NNFSKMAEEK LTHKMEANKE NREAQMAAKL ERLREKDKHI EEVRKNKESK DPADETEAD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards