About Transmembrane protein 11, mitochondrial
Transmembrane protein 11, mitochondrial (TMEM11) is a protein
from Homo sapiens identified by UniProt accession
P17152, 192 residues long.
MolForge cross-references it against 0 known binders and
61 disease associations.
Target properties
| Protein name | Transmembrane protein 11, mitochondrial |
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| UniProt accession | P17152 |
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| Gene | TMEM11 |
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| Organism | Homo sapiens |
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| Length | 192 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (61)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- hemoglobin measurement · score 0.34
- uric acid measurement · score 0.27
- hematocrit · score 0.24
- urate measurement · score 0.23
- myeloid white cell count · score 0.10
- neutrophil count · score 0.09
- left ventricular noncompaction · score 0.06
- hemoglobin E-beta-thalassemia syndrome · score 0.05
- IRIDA syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P17152-F1 | alphafold | PREDICTED | 78.80 | — |
Amino-acid sequence (192 residues)
MAAWGRRRLG PGSSGGSARE RVSLSATDCY IVHEIYNGEN AQDQFEYELE QALEAQYKYI VIEPTRIGDE TARWITVGNC LHKTAVLAGT ACLFTPLALP LDYSHYISLP AGVLSLACCT LYGISWQFDP CCKYQVEYDA YKLSRLPLHT LTSSTPVVLV RKDDLHRKRL HNTIALAALV YCVKKIYELY AV
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