Galanin peptides (GAL)

About Galanin peptides

Galanin peptides (GAL) is a protein from Homo sapiens identified by UniProt accession P22466, 123 residues long. MolForge cross-references it against 0 known binders and 413 disease associations.

Target properties

Protein name	Galanin peptides
UniProt accession	P22466
Gene	GAL
Organism	Homo sapiens
Length	123 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (413)

Diseases linked to this target (Open Targets).

temporal lobe epilepsy · score 0.50
neurodegenerative disease · score 0.46
autosomal dominant epilepsy with auditory features · score 0.41
body height · score 0.28
serum metabolite measurement · score 0.21
Abdominal pain · score 0.20
Headache · score 0.20
Limb pain · score 0.20
head and neck squamous cell carcinoma · score 0.19
breast adenocarcinoma · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P22466-F1	alphafold	PREDICTED	66.57	—

Amino-acid sequence (123 residues)

MARGSALLLA SLLLAAALSA SAGLWSPAKE KRGWTLNSAG YLLGPHAVGN HRSFSDKNGL TSKRELRPED DMKPGSFDRS IPENNIMRTI IEFLSFLHLK EAGALDRLLD LPAAASSEDI ERS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards