Cornifin-B (SPRR1B)

About Cornifin-B

Cornifin-B (SPRR1B) is a protein from Homo sapiens identified by UniProt accession P22528, 89 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.

Target properties

Protein name	Cornifin-B
UniProt accession	P22528
Gene	SPRR1B
Organism	Homo sapiens
Length	89 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (90)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.22
ovarian cancer · score 0.18
psoriasis · score 0.10
lung adenocarcinoma · score 0.08
non-small cell lung carcinoma · score 0.07
pentosuria · score 0.06
iminoglycinuria · score 0.06
cystathioninuria · score 0.06
beta-aminoisobutyric acid, urinary excretion of · score 0.06
phosphohydroxylysinuria · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P22528-F1	alphafold	PREDICTED	70.11	—

Amino-acid sequence (89 residues)

MSSQQQKQPC TPPPQLQQQQ VKQPCQPPPQ EPCIPKTKEP CHPKVPEPCH PKVPEPCQPK VPEPCHPKVP EPCPSIVTPA PAQQKTKQK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards