About Myeloblastin
Myeloblastin (PRTN3) is a protein
from Homo sapiens identified by UniProt accession
P24158, 256 residues long.
MolForge cross-references it against 0 known binders and
585 disease associations.
Target properties
| Protein name | Myeloblastin |
|---|
| UniProt accession | P24158 |
|---|
| Gene | PRTN3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 256 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (585)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.37
- basophil count · score 0.31
- monocyte count · score 0.29
- monocyte percentage of leukocytes · score 0.26
- Myopia · score 0.24
- age at onset · score 0.24
- basophil percentage of leukocytes · score 0.24
- anti-neutrophil antibody associated vasculitis · score 0.21
- protein measurement · score 0.21
- cutaneous melanoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P24158-F1 | alphafold | PREDICTED | 89.54 | — |
Amino-acid sequence (256 residues)
MAHRPPSPAL ASVLLALLLS GAARAAEIVG GHEAQPHSRP YMASLQMRGN PGSHFCGGTL IHPSFVLTAA HCLRDIPQRL VNVVLGAHNV RTQEPTQQHF SVAQVFLNNY DAENKLNDVL LIQLSSPANL SASVATVQLP QQDQPVPHGT QCLAMGWGRV GAHDPPAQVL QELNVTVVTF FCRPHNICTF VPRRKAGICF GDSGGPLICD GIIQGIDSFV IWGCATRLFP DFFTRVALYV DWIRSTLRRV EAKGRP
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