Large ribosomal subunit protein eL13 (RPL13)

About Large ribosomal subunit protein eL13

Large ribosomal subunit protein eL13 (RPL13) is a protein from Homo sapiens identified by UniProt accession P26373, 211 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL13
UniProt accession	P26373
Gene	RPL13
Organism	Homo sapiens
Length	211 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (63)

Diseases linked to this target (Open Targets).

spondyloepimetaphyseal dysplasia, Isidor-Toutain type · score 0.69
Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
spondyloepimetaphyseal dysplasia, matrilin-3 type · score 0.47
influenza · score 0.46
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
peak expiratory flow · score 0.21
neurodegenerative disease · score 0.20
genetic disorder · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P26373-F1	alphafold	PREDICTED	95.35	—

Amino-acid sequence (211 residues)

MAPSRNGMVL KPHFHKDWQR RVATWFNQPA RKIRRRKARQ AKARRIAPRP ASGPIRPIVR CPTVRYHTKV RAGRGFSLEE LRVAGIHKKV ARTIGISVDP RRRNKSTESL QANVQRLKEY RSKLILFPRK PSAPKKGDSS AEELKLATQL TGPVMPVRNV YKKEKARVIT EEEKNFKAFA SLRMARANAR LFGIRAKRAK EAAEQDVEKK K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards