About Stomatin
Stomatin (STOM) is a protein
from Homo sapiens identified by UniProt accession
P27105, 288 residues long.
MolForge cross-references it against 0 known binders and
103 disease associations.
Target properties
| Protein name | Stomatin |
|---|
| UniProt accession | P27105 |
|---|
| Gene | STOM |
|---|
| Organism | Homo sapiens |
|---|
| Length | 288 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (103)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.42
- mean platelet volume · score 0.38
- hemoglobin A1 measurement · score 0.34
- neurodegenerative disease · score 0.33
- HbA1c measurement · score 0.31
- mean reticulocyte volume · score 0.31
- mean corpuscular hemoglobin concentration · score 0.31
- breast adenocarcinoma · score 0.16
- neutrophil percentage of leukocytes · score 0.15
- red blood cell density measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P27105-F1 | alphafold | PREDICTED | 84.34 | — |
Amino-acid sequence (288 residues)
MAEKRHTRDS EAQRLPDSFK DSPSKGLGPC GWILVAFSFL FTVITFPISI WMCIKIIKEY ERAIIFRLGR ILQGGAKGPG LFFILPCTDS FIKVDMRTIS FDIPPQEILT KDSVTISVDG VVYYRVQNAT LAVANITNAD SATRLLAQTT LRNVLGTKNL SQILSDREEI AHNMQSTLDD ATDAWGIKVE RVEIKDVKLP VQLQRAMAAE AEASREARAK VIAAEGEMNA SRALKEASMV ITESPAALQL RYLQTLTTIA AEKNSTIVFP LPIDMLQGII GAKHSHLG
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