ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38)

About ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) is a protein from Homo sapiens identified by UniProt accession P28907, 300 residues long. MolForge cross-references it against 0 known binders and 794 disease associations.

Target properties

Protein name	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
UniProt accession	P28907
Gene	CD38
Organism	Homo sapiens
Length	300 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (3)

DrugCentral-linked approved drugs that act on this protein.

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P28907-F1	alphafold	PREDICTED	90.89	—

Amino-acid sequence (300 residues)

MANCEFSPVS GDKPCCRLSR RAQLCLGVSI LVLILVVVLA VVVPRWRQQW SGPGTTKRFP ETVLARCVKY TEIHPEMRHV DCQSVWDAFK GAFISKHPCN ITEEDYQPLM KLGTQTVPCN KILLWSRIKD LAHQFTQVQR DMFTLEDTLL GYLADDLTWC GEFNTSKINY QSCPDWRKDC SNNPVSVFWK TVSRRFAEAA CDVVHVMLNG SRSKIFDKNS TFGSVEVHNL QPEKVQTLEA WVIHGGREDS RDLCQDPTIK ELESIISKRN IQFSCKNIYR PDKFLQCVKN PEDSSCTSEI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards