Flavin reductase (NADPH) (BLVRB)

About Flavin reductase (NADPH)

Flavin reductase (NADPH) (BLVRB) is a protein from Homo sapiens identified by UniProt accession P30043, 206 residues long. MolForge cross-references it against 0 known binders and 101 disease associations.

Target properties

Protein name	Flavin reductase (NADPH)
UniProt accession	P30043
Gene	BLVRB
Organism	Homo sapiens
Length	206 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (7)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (101)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.44
reticulocyte measurement · score 0.42
bilirubin measurement · score 0.28
HbA1c measurement · score 0.28
mean reticulocyte volume · score 0.25
neutrophil percentage of leukocytes · score 0.19
diastolic blood pressure · score 0.18
body height · score 0.15
granulocyte percentage of myeloid white cells · score 0.14
monocyte percentage of leukocytes · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P30043-F1	alphafold	PREDICTED	97.72	—

Amino-acid sequence (206 residues)

MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards