About Transmembrane 4 L6 family member 1
Transmembrane 4 L6 family member 1 (TM4SF1) is a protein
from Homo sapiens identified by UniProt accession
P30408, 202 residues long.
MolForge cross-references it against 0 known binders and
109 disease associations.
Target properties
| Protein name | Transmembrane 4 L6 family member 1 |
|---|
| UniProt accession | P30408 |
|---|
| Gene | TM4SF1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 202 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (109)
Diseases linked to this target (Open Targets).
- serum alanine aminotransferase measurement · score 0.34
- aspartate aminotransferase measurement · score 0.31
- serum gamma-glutamyl transferase measurement · score 0.26
- platelet crit · score 0.26
- Red cell distribution width · score 0.22
- platelet count · score 0.12
- cancer · score 0.10
- platelet component distribution width · score 0.10
- hepatocellular carcinoma · score 0.10
- gonorrhea · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P30408-F1 | alphafold | PREDICTED | 80.58 | — |
Amino-acid sequence (202 residues)
MCYGKCARCI GHSLVGLALL CIAANILLYF PNGETKYASE NHLSRFVWFF SGIVGGGLLM LLPAFVFIGL EQDDCCGCCG HENCGKRCAM LSSVLAALIG IAGSGYCVIV AALGLAEGPL CLDSLGQWNY TFASTEGQYL LDTSTWSECT EPKHIVEWNV SLFSILLALG GIEFILCLIQ VINGVLGGIC GFCCSHQQQY DC
Explore Transmembrane 4 L6 family member 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets