About Sorcin
Sorcin (SRI) is a protein
from Homo sapiens identified by UniProt accession
P30626, 198 residues long.
MolForge cross-references it against 0 known binders and
144 disease associations.
Target properties
| Protein name | Sorcin |
|---|
| UniProt accession | P30626 |
|---|
| Gene | SRI |
|---|
| Organism | Homo sapiens |
|---|
| Length | 198 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (144)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.34
- appendicular lean mass · score 0.11
- MODY · score 0.10
- hepatocellular carcinoma · score 0.10
- neoplasm · score 0.08
- blood protein measurement · score 0.08
- type 2 diabetes mellitus · score 0.08
- type 1 diabetes mellitus · score 0.06
- diabetes mellitus, transient neonatal, 2 · score 0.06
- hyperinsulinism due to INSR deficiency · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P30626-F1 | alphafold | PREDICTED | 84.88 | — |
Amino-acid sequence (198 residues)
MAYPGHPGAG GGYYPGGYGG APGGPAFPGQ TQDPLYGYFA AVAGQDGQID ADELQRCLTQ SGIAGGYKPF NLETCRLMVS MLDRDMSGTM GFNEFKELWA VLNGWRQHFI SFDTDRSGTV DPQELQKALT TMGFRLSPQA VNSIAKRYST NGKITFDDYI ACCVKLRALT DSFRRRDTAQ QGVVNFPYDD FIQCVMSV
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