About Stress-induced-phosphoprotein 1
Stress-induced-phosphoprotein 1 (STIP1) is a protein
from Homo sapiens identified by UniProt accession
P31948, 543 residues long.
MolForge cross-references it against 0 known binders and
108 disease associations.
Target properties
| Protein name | Stress-induced-phosphoprotein 1 |
|---|
| UniProt accession | P31948 |
|---|
| Gene | STIP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 543 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (108)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- mean platelet volume · score 0.26
- monocyte count · score 0.15
- late-onset Alzheimers disease · score 0.14
- cancer · score 0.09
- neoplasm · score 0.09
- monocyte percentage of leukocytes · score 0.09
- hepatocellular carcinoma · score 0.09
- diet measurement · score 0.08
- endometriosis · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P31948-F1 | alphafold | PREDICTED | 89.76 | — |
Amino-acid sequence (543 residues)
MEQVNELKEK GNKALSVGNI DDALQCYSEA IKLDPHNHVL YSNRSAAYAK KGDYQKAYED GCKTVDLKPD WGKGYSRKAA ALEFLNRFEE AKRTYEEGLK HEANNPQLKE GLQNMEARLA ERKFMNPFNM PNLYQKLESD PRTRTLLSDP TYRELIEQLR NKPSDLGTKL QDPRIMTTLS VLLGVDLGSM DEEEEIATPP PPPPPKKETK PEPMEEDLPE NKKQALKEKE LGNDAYKKKD FDTALKHYDK AKELDPTNMT YITNQAAVYF EKGDYNKCRE LCEKAIEVGR ENREDYRQIA KAYARIGNSY FKEEKYKDAI HFYNKSLAEH RTPDVLKKCQ QAEKILKEQE RLAYINPDLA LEEKNKGNEC FQKGDYPQAM KHYTEAIKRN PKDAKLYSNR AACYTKLLEF QLALKDCEEC IQLEPTFIKG YTRKAAALEA MKDYTKAMDV YQKALDLDSS CKEAADGYQR CMMAQYNRHD SPEDVKRRAM ADPEVQQIMS DPAMRLILEQ MQKDPQALSE HLKNPVIAQK IQKLMDVGLI AIR
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