About Interferon alpha-8
Interferon alpha-8 (IFNA8) is a protein
from Homo sapiens identified by UniProt accession
P32881, 189 residues long.
MolForge cross-references it against 0 known binders and
45 disease associations.
Target properties
| Protein name | Interferon alpha-8 |
|---|
| UniProt accession | P32881 |
|---|
| Gene | IFNA8 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 189 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (45)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- chronic lymphocytic leukemia · score 0.14
- systemic lupus erythematosus · score 0.11
- hypothyroidism · score 0.06
- myxedema · score 0.05
- endocrine system disease · score 0.05
- diabetes mellitus · score 0.05
- Thyroid preparation use measurement · score 0.05
- squamous cell lung carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P32881-F1 | alphafold | PREDICTED | 84.61 | — |
Amino-acid sequence (189 residues)
MALTFYLLVA LVVLSYKSFS SLGCDLPQTH SLGNRRALIL LAQMRRISPF SCLKDRHDFE FPQEEFDDKQ FQKAQAISVL HEMIQQTFNL FSTKDSSAAL DETLLDEFYI ELDQQLNDLE SCVMQEVGVI ESPLMYEDSI LAVRKYFQRI TLYLTEKKYS SCAWEVVRAE IMRSFSLSIN LQKRLKSKE
Explore Interferon alpha-8 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets