Lymphocyte-specific protein 1 (LSP1)

About Lymphocyte-specific protein 1

Lymphocyte-specific protein 1 (LSP1) is a protein from Homo sapiens identified by UniProt accession P33241, 339 residues long. MolForge cross-references it against 0 known binders and 139 disease associations.

Target properties

Protein name	Lymphocyte-specific protein 1
UniProt accession	P33241
Gene	LSP1
Organism	Homo sapiens
Length	339 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (139)

Diseases linked to this target (Open Targets).

systolic blood pressure · score 0.43
diastolic blood pressure · score 0.43
alcohol drinking · score 0.43
mean arterial pressure · score 0.42
pulse pressure measurement · score 0.42
hypertension · score 0.39
Agents acting on the renin-angiotensin system use measurement · score 0.37
monocyte count · score 0.37
breast carcinoma · score 0.35
lymphocyte count · score 0.35

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P33241-F1	alphafold	PREDICTED	59.52	—

Amino-acid sequence (339 residues)

MAEASSDPGA EEREELLGPT AQWSVEDEEE AVHEQCQHER DRQLQAQDEE GGGHVPERPK QEMLLSLKPS EAPELDEDEG FGDWSQRPEQ RQQHEGAQGA LDSGEPPQCR SPEGEQEDRP GLHAYEKEDS DEVHLEELSL SKEGPGPEDT VQDNLGAAGA EEEQEEHQKC QQPRTPSPLV LEGTIEQSSP PLSPTTKLID RTESLNRSIE KSNSVKKSQP DLPISKIDQW LEQYTQAIET AGRTPKLARQ ASIELPSMAV ASTKSRWETG EVQAQSAAKT PSCKDIVAGD MSKKSLWEQK GGSKTSSTIK STPSGKRYKF VATGHGKYEK VLVEGGPAP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards