Cornifin-A (SPRR1A)

About Cornifin-A

Cornifin-A (SPRR1A) is a protein from Homo sapiens identified by UniProt accession P35321, 89 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.

Target properties

Protein name	Cornifin-A
UniProt accession	P35321
Gene	SPRR1A
Organism	Homo sapiens
Length	89 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (110)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.23
breast adenocarcinoma · score 0.22
prostate adenocarcinoma · score 0.21
head and neck squamous cell carcinoma · score 0.19
neuroblastoma · score 0.13
urinary bladder cancer · score 0.11
attention deficit hyperactivity disorder · score 0.09
schizophrenia 15 · score 0.07
attention deficit-hyperactivity disorder 8 · score 0.07
Fuchs endothelial corneal dystrophy · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P35321-F1	alphafold	PREDICTED	69.50	—

Amino-acid sequence (89 residues)

MNSQQQKQPC TPPPQPQQQQ VKQPCQPPPQ EPCIPKTKEP CHPKVPEPCH PKVPEPCQPK VPEPCQPKVP EPCPSTVTPA PAQQKTKQK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards