Somatostatin receptor type 5 (SSTR5)

About Somatostatin receptor type 5

Somatostatin receptor type 5 (SSTR5) is a protein from Homo sapiens identified by UniProt accession P35346, 364 residues long. MolForge cross-references it against 0 known binders and 304 disease associations.

Target properties

Protein name	Somatostatin receptor type 5
UniProt accession	P35346
Gene	SSTR5
Organism	Homo sapiens
Length	364 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (6)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (304)

Diseases linked to this target (Open Targets).

acromegaly · score 0.61
neoplasm · score 0.60
neuroendocrine neoplasm · score 0.59
carcinoid tumor · score 0.56
carcinoid syndrome · score 0.56
IGF-1 measurement · score 0.55
digestive system neuroendocrine neoplasm · score 0.54
obesity · score 0.51
cirrhosis of liver · score 0.50
esophageal varices · score 0.49

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P35346-F1	alphafold	PREDICTED	81.23	—

Amino-acid sequence (364 residues)

MEPLFPASTP SWNASSPGAA SGGGDNRTLV GPAPSAGARA VLVPVLYLLV CAAGLGGNTL VIYVVLRFAK MKTVTNIYIL NLAVADVLYM LGLPFLATQN AASFWPFGPV LCRLVMTLDG VNQFTSVFCL TVMSVDRYLA VVHPLSSARW RRPRVAKLAS AAAWVLSLCM SLPLLVFADV QEGGTCNASW PEPVGLWGAV FIIYTAVLGF FAPLLVICLC YLLIVVKVRA AGVRVGCVRR RSERKVTRMV LVVVLVFAGC WLPFFTVNIV NLAVALPQEP ASAGLYFFVV ILSYANSCAN PVLYGFLSDN FRQSFQKVLC LRKGSGAKDA DATEPRPDRI RQQQEATPPA HRAAANGLMQ TSKL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards