About Signal recognition particle 14 kDa protein
Signal recognition particle 14 kDa protein (SRP14) is a protein
from Homo sapiens identified by UniProt accession
P37108, 136 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Signal recognition particle 14 kDa protein |
|---|
| UniProt accession | P37108 |
|---|
| Gene | SRP14 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 136 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- reticulocyte count · score 0.35
- serum alanine aminotransferase measurement · score 0.35
- aspartate aminotransferase measurement · score 0.33
- serum albumin measurement · score 0.31
- calcium measurement · score 0.31
- serum gamma-glutamyl transferase measurement · score 0.25
- ulcerative colitis · score 0.23
- reticulocyte measurement · score 0.23
- platelet component distribution width · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P37108-F1 | alphafold | PREDICTED | 75.23 | — |
Amino-acid sequence (136 residues)
MVLLESEQFL TELTRLFQKC RTSGSVYITL KKYDGRTKPI PKKGTVEGFE PADNKCLLRA TDGKKKISTV VSSKEVNKFQ MAYSNLLRAN MDGLKKRDKK NKTKKTKAAA AAAAAAPAAA ATAPTTAATT AATAAQ
Explore Signal recognition particle 14 kDa protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets