About Tumor necrosis factor ligand superfamily member 9
Tumor necrosis factor ligand superfamily member 9 (TNFSF9) is a protein
from Homo sapiens identified by UniProt accession
P41273, 254 residues long.
MolForge cross-references it against 0 known binders and
163 disease associations.
Target properties
| Protein name | Tumor necrosis factor ligand superfamily member 9 |
|---|
| UniProt accession | P41273 |
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| Gene | TNFSF9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 254 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (163)
Diseases linked to this target (Open Targets).
- depressive disorder · score 0.17
- bone density · score 0.15
- urate measurement · score 0.15
- neurodegenerative disease · score 0.11
- neoplasm · score 0.10
- pachyonychia congenita · score 0.08
- colon carcinoma · score 0.06
- Chronic mucocutaneous candidosis · score 0.05
- hepatocellular carcinoma · score 0.05
- atherosclerosis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P41273-F1 | alphafold | PREDICTED | 76.63 | — |
Amino-acid sequence (254 residues)
MEYASDASLD PEAPWPPAPR ARACRVLPWA LVAGLLLLLL LAAACAVFLA CPWAVSGARA SPGSAASPRL REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE
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