Translocon-associated protein subunit beta (SSR2)

About Translocon-associated protein subunit beta

Translocon-associated protein subunit beta (SSR2) is a protein from Homo sapiens identified by UniProt accession P43308, 183 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Translocon-associated protein subunit beta
UniProt accession	P43308
Gene	SSR2
Organism	Homo sapiens
Length	183 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
myeloid white cell count · score 0.12
hepatocellular carcinoma · score 0.10
risk-taking behaviour · score 0.07
neoplasm · score 0.06
body mass index · score 0.06
Hepatic fibrosis · score 0.05
Truncus arteriosus · score 0.03
testosterone measurement · score 0.03
hemoglobin measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P43308-F1	alphafold	PREDICTED	91.81	—

Amino-acid sequence (183 residues)

MRLLSFVVLA LFAVTQAEEG ARLLASKSLL NRYAVEGRDL TLQYNIYNVG SSAALDVELS DDSFPPEDFG IVSGMLNVKW DRIAPASNVS HTVVLRPLKA GYFNFTSATI TYLAQEDGPV VIGSTSAPGQ GGILAQREFD RRFSPHFLDW AAFGVMTLPS IGIPLLLWYS SKRKYDTPKT KKN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards