Signal recognition particle 9 kDa protein (SRP9)

About Signal recognition particle 9 kDa protein

Signal recognition particle 9 kDa protein (SRP9) is a protein from Homo sapiens identified by UniProt accession P49458, 86 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.

Target properties

Protein name	Signal recognition particle 9 kDa protein
UniProt accession	P49458
Gene	SRP9
Organism	Homo sapiens
Length	86 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (50)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.54
mean corpuscular volume · score 0.24
mean reticulocyte volume · score 0.24
leukocyte count · score 0.23
lymphocyte count · score 0.23
monocyte count · score 0.22
neuroticism measurement · score 0.21
Red cell distribution width · score 0.20
platelet component distribution width · score 0.18
platelet crit · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P49458-F1	alphafold	PREDICTED	90.28	—

Amino-acid sequence (86 residues)

MPQYQTWEEF SRAAEKLYLA DPMKARVVLK YRHSDGNLCV KVTDDLVCLV YKTDQAQDVK KIEKFHSQLM RLMVAKEARN VTMETE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards