Sulfotransferase 1E1 (SULT1E1)

About Sulfotransferase 1E1

Sulfotransferase 1E1 (SULT1E1) is a protein from Homo sapiens identified by UniProt accession P49888, 294 residues long. MolForge cross-references it against 0 known binders and 205 disease associations.

Target properties

Protein name	Sulfotransferase 1E1
UniProt accession	P49888
Gene	SULT1E1
Organism	Homo sapiens
Length	294 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (205)

Diseases linked to this target (Open Targets).

sex hormone-binding globulin measurement · score 0.32
heel bone mineral density · score 0.19
uterine fibroid · score 0.18
Uterine leiomyoma · score 0.16
azoospermia · score 0.07
neoplasm · score 0.07
isolated congenital hypogonadotropic hypogonadism · score 0.07
Testicular regression syndrome · score 0.06
Barrett's esophagus · score 0.06
46,XX testicular disorder of sex development · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P49888-F1	alphafold	PREDICTED	97.22	—

Amino-acid sequence (294 residues)

MNSELDYYEK FEEVHGILMY KDFVKYWDNV EAFQARPDDL VIATYPKSGT TWVSEIVYMI YKEGDVEKCK EDVIFNRIPF LECRKENLMN GVKQLDEMNS PRIVKTHLPP ELLPASFWEK DCKIIYLCRN AKDVAVSFYY FFLMVAGHPN PGSFPEFVEK FMQGQVPYGS WYKHVKSWWE KGKSPRVLFL FYEDLKEDIR KEVIKLIHFL ERKPSEELVD RIIHHTSFQE MKNNPSTNYT TLPDEIMNQK LSPFMRKGIT GDWKNHFTVA LNEKFDKHYE QQMKESTLKF RTEI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards