About Sulfotransferase 1A1
Sulfotransferase 1A1 (SULT1A1) is a protein
from Homo sapiens identified by UniProt accession
P50225, 295 residues long.
MolForge cross-references it against 0 known binders and
219 disease associations.
Target properties
| Protein name | Sulfotransferase 1A1 |
| UniProt accession | P50225 |
| Gene | SULT1A1 |
| Organism | Homo sapiens |
| Length | 295 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (219)
Diseases linked to this target (Open Targets).
- risk-taking behaviour · score 0.24
- obese body mass index status · score 0.24
- C-reactive protein measurement · score 0.22
- cystatin C measurement · score 0.21
- platelet count · score 0.09
- type 1 diabetes mellitus · score 0.09
- alcohol consumption measurement · score 0.09
- allergic rhinitis · score 0.09
- BMI-adjusted waist circumference · score 0.08
- platelet crit · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P50225-F1 | alphafold | PREDICTED | 96.73 | — |
Amino-acid sequence (295 residues)
MELIQDTSRP PLEYVKGVPL IKYFAEALGP LQSFQARPDD LLISTYPKSG TTWVSQILDM IYQGGDLEKC HRAPIFMRVP FLEFKAPGIP SGMETLKDTP APRLLKTHLP LALLPQTLLD QKVKVVYVAR NAKDVAVSYY HFYHMAKVHP EPGTWDSFLE KFMVGEVSYG SWYQHVQEWW ELSRTHPVLY LFYEDMKENP KREIQKILEF VGRSLPEETV DFVVQHTSFK EMKKNPMTNY TTVPQEFMDH SISPFMRKGM AGDWKTTFTV AQNERFDADY AEKMAGCSLS FRSEL
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