Sulfotransferase 1A1 (SULT1A1)

Homo sapiens — UniProt P50225

Gene: SULT1A1Homo sapiensSwissProt reviewed

About Sulfotransferase 1A1

Sulfotransferase 1A1 (SULT1A1) is a protein from Homo sapiens identified by UniProt accession P50225, 295 residues long. MolForge cross-references it against 0 known binders and 219 disease associations.

Target properties

Protein nameSulfotransferase 1A1
UniProt accessionP50225
GeneSULT1A1
OrganismHomo sapiens
Length295 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (219)

Diseases linked to this target (Open Targets).

  • risk-taking behaviour · score 0.24
  • obese body mass index status · score 0.24
  • C-reactive protein measurement · score 0.22
  • cystatin C measurement · score 0.21
  • platelet count · score 0.09
  • type 1 diabetes mellitus · score 0.09
  • alcohol consumption measurement · score 0.09
  • allergic rhinitis · score 0.09
  • BMI-adjusted waist circumference · score 0.08
  • platelet crit · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P50225-F1alphafoldPREDICTED96.73—

Amino-acid sequence (295 residues)

MELIQDTSRP PLEYVKGVPL IKYFAEALGP LQSFQARPDD LLISTYPKSG TTWVSQILDM IYQGGDLEKC HRAPIFMRVP FLEFKAPGIP SGMETLKDTP APRLLKTHLP LALLPQTLLD QKVKVVYVAR NAKDVAVSYY HFYHMAKVHP EPGTWDSFLE KFMVGEVSYG SWYQHVQEWW ELSRTHPVLY LFYEDMKENP KREIQKILEF VGRSLPEETV DFVVQHTSFK EMKKNPMTNY TTVPQEFMDH SISPFMRKGM AGDWKTTFTV AQNERFDADY AEKMAGCSLS FRSEL

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Quick facts

UniProtP50225
GeneSULT1A1
OrganismHomo sapiens
Length295
Binders0
Diseases219
View on UniProt