About Sulfotransferase 1A2
Sulfotransferase 1A2 (SULT1A2) is a protein
from Homo sapiens identified by UniProt accession
P50226, 295 residues long.
MolForge cross-references it against 0 known binders and
147 disease associations.
Target properties
| Protein name | Sulfotransferase 1A2 |
|---|
| UniProt accession | P50226 |
|---|
| Gene | SULT1A2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 295 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (147)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- platelet count · score 0.32
- lysosomal storage disease · score 0.28
- multiple sclerosis · score 0.28
- Alzheimer disease · score 0.28
- Parkinson disease · score 0.28
- type 1 diabetes mellitus · score 0.24
- alcohol consumption measurement · score 0.22
- lean body mass · score 0.21
- self reported educational attainment · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P50226-F1 | alphafold | PREDICTED | 96.72 | — |
Amino-acid sequence (295 residues)
MELIQDISRP PLEYVKGVPL IKYFAEALGP LQSFQARPDD LLISTYPKSG TTWVSQILDM IYQGGDLEKC HRAPIFMRVP FLEFKVPGIP SGMETLKNTP APRLLKTHLP LALLPQTLLD QKVKVVYVAR NAKDVAVSYY HFYHMAKVYP HPGTWESFLE KFMAGEVSYG SWYQHVQEWW ELSRTHPVLY LFYEDMKENP KREIQKILEF VGRSLPEETV DLMVEHTSFK EMKKNPMTNY TTVRREFMDH SISPFMRKGM AGDWKTTFTV AQNERFDADY AKKMAGCSLS FRSEL
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