About Hsc70-interacting protein
Hsc70-interacting protein (ST13) is a protein
from Homo sapiens identified by UniProt accession
P50502, 369 residues long.
MolForge cross-references it against 0 known binders and
65 disease associations.
Target properties
| Protein name | Hsc70-interacting protein |
|---|
| UniProt accession | P50502 |
|---|
| Gene | ST13 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 369 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (65)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- low density lipoprotein cholesterol measurement · score 0.32
- C-reactive protein measurement · score 0.29
- apolipoprotein B measurement · score 0.23
- total cholesterol measurement · score 0.23
- vitamin D measurement · score 0.21
- nephronophthisis · score 0.12
- bipolar disorder · score 0.08
- mean platelet volume · score 0.08
- platelet count · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P50502-F1 | alphafold | PREDICTED | 81.19 | — |
Amino-acid sequence (369 residues)
MDPRKVNELR AFVKMCKQDP SVLHTEEMRF LREWVESMGG KVPPATQKAK SEENTKEEKP DSKKVEEDLK ADEPSSEESD LEIDKEGVIE PDTDAPQEMG DENAEITEEM MDQANDKKVA AIEALNDGEL QKAIDLFTDA IKLNPRLAIL YAKRASVFVK LQKPNAAIRD CDRAIEINPD SAQPYKWRGK AHRLLGHWEE AAHDLALACK LDYDEDASAM LKEVQPRAQK IAEHRRKYER KREEREIKER IERVKKAREE HERAQREEEA RRQSGAQYGS FPGGFPGGMP GNFPGGMPGM GGGMPGMAGM PGLNEILSDP EVLAAMQDPE VMVAFQDVAQ NPANMSKYQS NPKVMNLISK LSAKFGGQA
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