About Protein Tob1
Protein Tob1 (TOB1) is a protein
from Homo sapiens identified by UniProt accession
P50616, 345 residues long.
MolForge cross-references it against 0 known binders and
131 disease associations.
Target properties
| Protein name | Protein Tob1 |
|---|
| UniProt accession | P50616 |
|---|
| Gene | TOB1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 345 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (131)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- osteoarthritis, hip · score 0.29
- protein measurement · score 0.19
- blood protein measurement · score 0.09
- gonorrhea · score 0.08
- inflammatory bowel disease · score 0.08
- non-small cell lung carcinoma · score 0.08
- esophageal squamous cell carcinoma · score 0.07
- neoplasm · score 0.07
- experimental autoimmune encephalomyelitis · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P50616-F1 | alphafold | PREDICTED | 66.01 | — |
Amino-acid sequence (345 residues)
MQLEIQVALN FIISYLYNKL PRRRVNIFGE ELERLLKKKY EGHWYPEKPY KGSGFRCIHI GEKVDPVIEQ ASKESGLDID DVRGNLPQDL SVWIDPFEVS YQIGEKGPVK VLYVDDNNEN GCELDKEIKN SFNPEAQVFM PISDPASSVS SSPSPPFGHS AAVSPTFMPR STQPLTFTTA TFAATKFGST KMKNSGRSNK VARTSPINLG LNVNDLLKQK AISSSMHSLY GLGLGSQQQP QQQQQPAQPP PPPPPPQQQQ QQKTSALSPN AKEFIFPNMQ GQGSSTNGMF PGDSPLNLSP LQYSNAFDVF AAYGGLNEKS FVDGLNFSLN NMQYSNQQFQ PVMAN
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