Translocon-associated protein subunit delta (SSR4)

About Translocon-associated protein subunit delta

Translocon-associated protein subunit delta (SSR4) is a protein from Homo sapiens identified by UniProt accession P51571, 173 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	Translocon-associated protein subunit delta
UniProt accession	P51571
Gene	SSR4
Organism	Homo sapiens
Length	173 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

SSR4-congenital disorder of glycosylation · score 0.76
neurodegenerative disease · score 0.32
genetic disorder · score 0.18
endometrial cancer · score 0.11
Miyoshi myopathy · score 0.02
Abnormal sperm morphology · score 0.01
lung adenocarcinoma · score 0.01
melanoma · score 0.01
colon adenocarcinoma · score 0.01
periodontitis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51571-F1	alphafold	PREDICTED	88.57	—

Amino-acid sequence (173 residues)

MAAMASLGAL ALLLLSSLSR CSAEACLEPQ ITPSYYTTSD AVISTETVFI VEISLTCKNR VQNMALYADV GGKQFPVTRG QDVGRYQVSW SLDHKSAHAG TYEVRFFDEE SYSLLRKAQR NNEDISIIPP LFTVSVDHRG TWNGPWVSTE VLAAAIGLVI YYLAFSAKSH IQA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards