About Sulfite oxidase, mitochondrial
Sulfite oxidase, mitochondrial (SUOX) is a protein
from Homo sapiens identified by UniProt accession
P51687, 545 residues long.
MolForge cross-references it against 0 known binders and
154 disease associations.
Target properties
| Protein name | Sulfite oxidase, mitochondrial |
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| UniProt accession | P51687 |
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| Gene | SUOX |
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| Organism | Homo sapiens |
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| Length | 545 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (154)
Diseases linked to this target (Open Targets).
- isolated sulfite oxidase deficiency · score 0.83
- genetic disorder · score 0.49
- type 1 diabetes mellitus · score 0.22
- childhood onset asthma · score 0.21
- asthma · score 0.20
- hypothyroidism · score 0.20
- eosinophil count · score 0.20
- autoimmune disease · score 0.19
- rheumatoid arthritis · score 0.18
- forced expiratory volume · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P51687-F1 | alphafold | PREDICTED | 84.69 | — |
Amino-acid sequence (545 residues)
MLLLHRAVVL RLQQACRLKS IPSRICIQAC STNDSFQPQR PSLTFSGDNS STQGWRVMGT LLGLGAVLAY QDHRCRAAQE STHIYTKEEV SSHTSPETGI WVTLGSEVFD VTEFVDLHPG GPSKLMLAAG GPLEPFWALY AVHNQSHVRE LLAQYKIGEL NPEDKVAPTV ETSDPYADDP VRHPALKVNS QRPFNAEPPP ELLTENYITP NPIFFTRNHL PVPNLDPDTY RLHVVGAPGG QSLSLSLDDL HNFPRYEITV TLQCAGNRRS EMTQVKEVKG LEWRTGAIST ARWAGARLCD VLAQAGHQLC ETEAHVCFEG LDSDPTGTAY GASIPLARAM DPEAEVLLAY EMNGQPLPRD HGFPVRVVVP GVVGARHVKW LGRVSVQPEE SYSHWQRRDY KGFSPSVDWE TVDFDSAPSI QELPVQSAIT EPRDGETVES GEVTIKGYAW SGGGRAVIRV DVSLDGGLTW QVAKLDGEEQ RPRKAWAWRL WQLKAPVPAG QKELNIVCKA VDDGYNVQPD TVAPIWNLRG VLSNAWHRVH VYVSP
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