About Zinc finger protein 135
Zinc finger protein 135 (ZNF135) is a protein
from Homo sapiens identified by UniProt accession
P52742, 658 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Zinc finger protein 135 |
|---|
| UniProt accession | P52742 |
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| Gene | ZNF135 |
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| Organism | Homo sapiens |
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| Length | 658 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (38)
Diseases linked to this target (Open Targets).
- Down syndrome · score 0.04
- mean corpuscular hemoglobin · score 0.03
- mean corpuscular hemoglobin concentration · score 0.02
- neoplasm · score 0.02
- cancer · score 0.01
- papillary thyroid carcinoma · score 0.01
- Autosomal dominant polycystic kidney disease · score 0.01
- psoriasis · score 0.01
- Sepsis · score 0.01
- benign prostatic hyperplasia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P52742-F1 | alphafold | PREDICTED | 73.63 | — |
Amino-acid sequence (658 residues)
MTPGVRVSTD PEQVTFEDVV VGFSQEEWGQ LKPAQRTLYR DVMLDTFRLL VSVGHWLPKP NVISLLEQEA ELWAVESRLP QGVYPDLETR PKVKLSVLKQ GISEEISNSV ILVERFLWDG LWYCRGEDTE GHWEWSCESL ESLAVPVAFT PVKTPVLEQW QRNGFGENIS LNPDLPHQPM TPERQSPHTW GTRGKREKPD LNVLQKTCVK EKPYKCQECG KAFSHSSALI EHHRTHTGER PYECHECLKG FRNSSALTKH QRIHTGEKPY KCTQCGRTFN QIAPLIQHQR THTGEKPYEC SECGKSFSFR SSFSQHERTH TGEKPYECSE CGKAFRQSIH LTQHLRIHTG EKPYQCGECG KAFSHSSSLT KHQRIHTGEK PYECHECGKA FTQITPLIQH QRTHTGEKPY ECGECGKAFS QSTLLTEHRR IHTGEKPYGC NECGKTFSHS SSLSQHERTH TGEKPYECSQ CGKAFRQSTH LTQHQRIHTG EKPYECNDCG KAFSHSSSLT KHQRIHTGEK PYECNQCGRA FSQLAPLIQH QRIHTGEKPY ECNQCGRAFS QSSLLIEHQR IHTKEKPYGC NECGKSFSHS SSLSQHERTH TGEKPYECHD CGKSFRQSTH LTQHRRIHTG EKPYACRDCG KAFTHSSSLT KHQRTHTG
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