About Ephrin-A4
Ephrin-A4 (EFNA4) is a protein
from Homo sapiens identified by UniProt accession
P52798, 201 residues long.
MolForge cross-references it against 0 known binders and
103 disease associations.
Target properties
| Protein name | Ephrin-A4 |
|---|
| UniProt accession | P52798 |
|---|
| Gene | EFNA4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 201 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (103)
Diseases linked to this target (Open Targets).
- serum urea measurement · score 0.38
- cutaneous melanoma · score 0.13
- hepatocellular carcinoma · score 0.10
- serum gamma-glutamyl transferase measurement · score 0.10
- neoplasm · score 0.08
- oral squamous cell carcinoma · score 0.08
- vein disorder · score 0.07
- Varicose veins · score 0.07
- serum albumin measurement · score 0.07
- cortical surface area measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P52798-F1 | alphafold | PREDICTED | 82.67 | — |
Amino-acid sequence (201 residues)
MRLLPLLRTV LWAAFLGSPL RGGSSLRHVV YWNSSNPRLL RGDAVVELGL NDYLDIVCPH YEGPGPPEGP ETFALYMVDW PGYESCQAEG PRAYKRWVCS LPFGHVQFSE KIQRFTPFSL GFEFLPGETY YYISVPTPES SGQCLRLQVS VCCKERKSES AHPVGSPGES GTSGWRGGDT PSPLCLLLLL LLLILRLLRI L
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