About Stanniocalcin-1
Stanniocalcin-1 (STC1) is a protein
from Homo sapiens identified by UniProt accession
P52823, 247 residues long.
MolForge cross-references it against 0 known binders and
267 disease associations.
Target properties
| Protein name | Stanniocalcin-1 |
|---|
| UniProt accession | P52823 |
|---|
| Gene | STC1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 247 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (267)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.41
- glomerular filtration rate · score 0.41
- creatinine measurement · score 0.40
- blood urea nitrogen measurement · score 0.37
- serum urea measurement · score 0.36
- uric acid measurement · score 0.34
- urinary albumin to creatinine ratio · score 0.33
- cystatin C measurement · score 0.32
- peak expiratory flow · score 0.30
- sitting height measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P52823-F1 | alphafold | PREDICTED | 78.88 | — |
Amino-acid sequence (247 residues)
MLQNSAVLLV LVISASATHE AEQNDSVSPR KSRVAAQNSA EVVRCLNSAL QVGCGAFACL ENSTCDTDGM YDICKSFLYS AAKFDTQGKA FVKESLKCIA NGVTSKVFLA IRRCSTFQRM IAEVQEECYS KLNVCSIAKR NPEAITEVVQ LPNHFSNRYY NRLVRSLLEC DEDTVSTIRD SLMEKIGPNM ASLFHILQTD HCAQTHPRAD FNRRRTNEPQ KLKVLLRNLR GEEDSPSHIK RTSHESA
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