Small ubiquitin-related modifier 3 (SUMO3)

About Small ubiquitin-related modifier 3

Small ubiquitin-related modifier 3 (SUMO3) is a protein from Homo sapiens identified by UniProt accession P55854, 103 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.

Target properties

Protein name	Small ubiquitin-related modifier 3
UniProt accession	P55854
Gene	SUMO3
Organism	Homo sapiens
Length	103 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (59)

Diseases linked to this target (Open Targets).

endometrial cancer · score 0.25
esophageal cancer · score 0.23
gastric adenocarcinoma · score 0.18
lung adenocarcinoma · score 0.18
Red cell distribution width · score 0.10
erythrocyte count · score 0.08
fragile X-associated tremor/ataxia syndrome · score 0.07
Huntington disease · score 0.06
high density lipoprotein cholesterol measurement · score 0.06
Helicobacter pylori infectious disease · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P55854-F1	alphafold	PREDICTED	81.04	—

Amino-acid sequence (103 residues)

MSEEKPKEGV KTENDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSMRQIRFR FDGQPINETD TPAQLEMEDE DTIDVFQQQT GGVPESSLAG HSF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards