About Transmembrane protein 33
Transmembrane protein 33 (TMEM33) is a protein
from Homo sapiens identified by UniProt accession
P57088, 247 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Transmembrane protein 33 |
|---|
| UniProt accession | P57088 |
|---|
| Gene | TMEM33 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 247 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (32)
Diseases linked to this target (Open Targets).
- alcohol consumption measurement · score 0.11
- cervical squamous cell carcinoma · score 0.07
- platelet crit · score 0.06
- unipolar depression · score 0.06
- attention deficit hyperactivity disorder · score 0.05
- autism spectrum disorder · score 0.05
- schizophrenia 15 · score 0.04
- acute kidney failure · score 0.03
- cancer · score 0.03
- type 1 diabetes mellitus · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P57088-F1 | alphafold | PREDICTED | 88.37 | — |
Amino-acid sequence (247 residues)
MADTTPNGPQ GAGAVQFMMT NKLDTAMWLS RLFTVYCSAL FVLPLLGLHE AASFYQRALL ANALTSALRL HQRLPHFQLS RAFLAQALLE DSCHYLLYSL IFVNSYPVTM SIFPVLLFSL LHAATYTKKV LDARGSNSLP LLRSVLDKLS ANQQNILKFI ACNEIFLMPA TVFMLFSGQG SLLQPFIYYR FLTLRYSSRR NPYCRTLFNE LRIVVEHIIM KPACPLFVRR LCLQSIAFIS RLAPTVP
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