About Synaptojanin-2-binding protein
Synaptojanin-2-binding protein (SYNJ2BP) is a protein
from Homo sapiens identified by UniProt accession
P57105, 145 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Synaptojanin-2-binding protein |
|---|
| UniProt accession | P57105 |
|---|
| Gene | SYNJ2BP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 145 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (38)
Diseases linked to this target (Open Targets).
- low density lipoprotein cholesterol measurement · score 0.38
- apolipoprotein B measurement · score 0.18
- alkaline phosphatase measurement · score 0.16
- aspartate aminotransferase measurement · score 0.16
- total cholesterol measurement · score 0.13
- response to statin · score 0.10
- prostate carcinoma · score 0.09
- hepatocellular carcinoma · score 0.07
- neoplasm · score 0.07
- cholesterol-ester transfer protein deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P57105-F1 | alphafold | PREDICTED | 78.73 | — |
Amino-acid sequence (145 residues)
MNGRVDYLVT EEEINLTRGP SGLGFNIVGG TDQQYVSNDS GIYVSRIKEN GAAALDGRLQ EGDKILSVNG QDLKNLLHQD AVDLFRNAGY AVSLRVQHRL QVQNGPIGHR GEGDPSGIPI FMVLVPVFAL TMVAAWAFMR YRQQL
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