About Ubiquitin-conjugating enzyme E2 K
Ubiquitin-conjugating enzyme E2 K (UBE2K) is a protein
from Homo sapiens identified by UniProt accession
P61086, 200 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | Ubiquitin-conjugating enzyme E2 K |
|---|
| UniProt accession | P61086 |
|---|
| Gene | UBE2K |
|---|
| Organism | Homo sapiens |
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| Length | 200 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- platelet count · score 0.35
- self reported educational attainment · score 0.33
- high density lipoprotein cholesterol measurement · score 0.32
- apolipoprotein A 1 measurement · score 0.29
- platelet crit · score 0.28
- insulin like growth factor measurement · score 0.24
- serum albumin measurement · score 0.24
- triglyceride measurement · score 0.22
- IGF-1 measurement · score 0.21
- sex hormone-binding globulin measurement · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P61086-F1 | alphafold | PREDICTED | 96.69 | — |
Amino-acid sequence (200 residues)
MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELR GEIAGPPDTP YEGGRYQLEI KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA EPDDPQDAVV ANQYKQNPEM FKQTARLWAH VYAGAPVSSP EYTKKIENLC AMGFDRNAVI VALSSKSWDV ETATELLLSN
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