Large ribosomal subunit protein uL24 (RPL26)

About Large ribosomal subunit protein uL24

Large ribosomal subunit protein uL24 (RPL26) is a protein from Homo sapiens identified by UniProt accession P61254, 145 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.

Target properties

Protein name	Large ribosomal subunit protein uL24
UniProt accession	P61254
Gene	RPL26
Organism	Homo sapiens
Length	145 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (66)

Diseases linked to this target (Open Targets).

Blackfan-Diamond anemia · score 0.65
Diamond-Blackfan anemia · score 0.58
Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
aniridia · score 0.09
diffuse large B-cell lymphoma · score 0.08
epilepsy · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61254-F1	alphafold	PREDICTED	92.87	—

Amino-acid sequence (145 residues)

MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG HYKGQQIGKV VQVYRKKYVI YIERVQREKA NGTTVHVGIH PSKVVITRLK LDKDRKKILE RKAKSRQVGK EKGKYKEETI EKMQE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards