Somatostatin (SST)

About Somatostatin

Somatostatin (SST) is a protein from Homo sapiens identified by UniProt accession P61278, 116 residues long. MolForge cross-references it against 0 known binders and 754 disease associations.

Target properties

Protein name	Somatostatin
UniProt accession	P61278
Gene	SST
Organism	Homo sapiens
Length	116 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (754)

Diseases linked to this target (Open Targets).

age at menarche · score 0.27
glioblastoma multiforme · score 0.27
breast adenocarcinoma · score 0.17
hemoglobin measurement · score 0.15
allergic rhinitis · score 0.14
triglyceride measurement · score 0.14
hematocrit · score 0.14
Eczematoid dermatitis · score 0.13
eosinophil count · score 0.13
waist-hip ratio · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61278-F1	alphafold	PREDICTED	65.79	—

Amino-acid sequence (116 residues)

MLSCRLQCAL AALSIVLALG CVTGAPSDPR LRQFLQKSLA AAAGKQELAK YFLAELLSEP NQTENDALEP EDLSQAAEQD EMRLELQRSA NSNPAMAPRE RKAGCKNFFW KTFTSC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards