Lysozyme C (LYZ)

About Lysozyme C

Lysozyme C (LYZ) is a protein from Homo sapiens identified by UniProt accession P61626, 148 residues long. MolForge cross-references it against 0 known binders and 825 disease associations.

Target properties

Protein name	Lysozyme C
UniProt accession	P61626
Gene	LYZ
Organism	Homo sapiens
Length	148 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (825)

Diseases linked to this target (Open Targets).

familial visceral amyloidosis · score 0.69
Familial renal amyloidosis · score 0.58
blood protein measurement · score 0.47
monocyte count · score 0.47
AL amyloidosis · score 0.46
C-reactive protein measurement · score 0.43
leukocyte count · score 0.42
monocyte percentage of leukocytes · score 0.41
ALys amyloidosis · score 0.37
myeloid white cell count · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61626-F1	alphafold	PREDICTED	94.07	—

Amino-acid sequence (148 residues)

MKALIVLGLV LLSVTVQGKV FERCELARTL KRLGMDGYRG ISLANWMCLA KWESGYNTRA TNYNAGDRST DYGIFQINSR YWCNDGKTPG AVNACHLSCS ALLQDNIADA VACAKRVVRD PQGIRAWVAW RNRCQNRDVR QYVQGCGV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards