Thymosin beta-4 (TMSB4X)

About Thymosin beta-4

Thymosin beta-4 (TMSB4X) is a protein from Homo sapiens identified by UniProt accession P62328, 44 residues long. MolForge cross-references it against 0 known binders and 208 disease associations.

Target properties

Protein name	Thymosin beta-4
UniProt accession	P62328
Gene	TMSB4X
Organism	Homo sapiens
Length	44 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (208)

Diseases linked to this target (Open Targets).

diffuse large B-cell lymphoma · score 0.52
neurodegenerative disease · score 0.46
non-Hodgkins lymphoma · score 0.37
lymphoma · score 0.26
multiple myeloma · score 0.19
lung carcinoma · score 0.19
prostate adenocarcinoma · score 0.18
cutaneous melanoma · score 0.18
gastric carcinoma · score 0.18
chronic lymphocytic leukemia · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62328-F1	alphafold	PREDICTED	80.79	—

Amino-acid sequence (44 residues)

MSDKPDMAEI EKFDKSKLKK TETQEKNPLP SKETIEQEKQ AGES

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards