Small ribosomal subunit protein eS25 (RPS25)

About Small ribosomal subunit protein eS25

Small ribosomal subunit protein eS25 (RPS25) is a protein from Homo sapiens identified by UniProt accession P62851, 125 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.

Target properties

Protein name	Small ribosomal subunit protein eS25
UniProt accession	P62851
Gene	RPS25
Organism	Homo sapiens
Length	125 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (57)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
Becker muscular dystrophy · score 0.29
endometrial cancer · score 0.27
qualitative or quantitative defects of dystrophin · score 0.26
aniridia · score 0.09
diffuse large B-cell lymphoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62851-F1	alphafold	PREDICTED	73.24	—

Amino-acid sequence (125 residues)

MPPKDDKKKK DAGKSAKKDK DPVNKSGGKA KKKKWSKGKV RDKLNNLVLF DKATYDKLCK EVPNYKLITP AVVSERLKIR GSLARAALQE LLSKGLIKLV SKHRAQVIYT RNTKGGDAPA AGEDA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards