Small ubiquitin-related modifier 1 (SUMO1)

About Small ubiquitin-related modifier 1

Small ubiquitin-related modifier 1 (SUMO1) is a protein from Homo sapiens identified by UniProt accession P63165, 101 residues long. MolForge cross-references it against 0 known binders and 250 disease associations.

Target properties

Protein name	Small ubiquitin-related modifier 1
UniProt accession	P63165
Gene	SUMO1
Organism	Homo sapiens
Length	101 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (250)

Diseases linked to this target (Open Targets).

orofacial cleft 10 · score 0.42
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
lung adenocarcinoma · score 0.29
breast adenocarcinoma · score 0.28
squamous cell lung carcinoma · score 0.25
aspartate aminotransferase measurement · score 0.19
cystatin C measurement · score 0.17
Red cell distribution width · score 0.13
mean corpuscular hemoglobin concentration · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P63165-F1	alphafold	PREDICTED	78.28	—

Amino-acid sequence (101 residues)

MSDQEAKPST EDLGDKKEGE YIKLKVIGQD SSEIHFKVKM TTHLKKLKES YCQRQGVPMN SLRFLFEGQR IADNHTPKEL GMEEEDVIEV YQEQTGGHST V

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards